Pharmacokinetics and clinical importance

2021-06-24 02:55 PM

Knowledge of pharmacokinetics guides patient drug selection based on the patient's medical condition, e.g. age, renal function

Concept

The field of pharmacology includes pharmacodynamics and pharmacokinetics.

Pharmacodynamics is the process by which a drug acts on the body. Describe the effect of a drug as well as side effects, how it works, in which organ system, which tissue, on which receptor, in what concentration… The effect of a drug can be altered by other drugs. other concurrent use or caused by a medical condition. Synergistic, synergistic, antagonistic, and other phenomena related to drug action are all described by pharmacodynamics.

Pharmacokinetics is the study of the effects of the body on drugs through four processes: absorption, distribution, metabolism, and elimination of drugs in the body.

The importance of drug pharmacokinetics

To achieve and maintain plasma drug concentrations to achieve the pharmacological effects of the drug, knowledge of the pharmacokinetics of the drug will help in the reasonable calculation:  

The dose of the drug used.

Frequency of giving medication.

Treatment time.

Usage route.

Knowledge of pharmacokinetics guides patient drug selection based on the patient's medical condition (e.g. age, renal function, etc.) and guidelines for optimal drug use (e.g. use medicine on an empty stomach…).