Problems with inappropriate antibiotic use

2021-06-23 02:21 PM

Not paying attention to adjusting the dose of aminoglycoside antibiotics, beta-lactams, for special groups of patients, elderly people, people with kidney failure, people with liver failure.

In a medical facility

The diagnosis of the disease was not correct because the doctor did not pay attention and did not accurately identify the bacteria causing the disease.

There is not enough information on the drug resistance situation of pathogenic bacteria locally and in the region.

Abuse of broad-spectrum antibiotics, encapsulating treatment.

Abuse of antibiotic combination or do not know the principles of antibiotic combination.

Not paying attention to adjusting the dose of aminoglycosides, beta-lactam antibiotics...for special groups of patients (elderly people, people with kidney failure, people with liver failure, children, pregnant women, lactating mothers...) .


Lack of treatment guidelines.

Doctors and pharmacists lack knowledge about rational drug use (clinical pharmacology, clinical pharmacology) or have not applied their knowledge to clinical practice.

Doctors lack updated information on rational drug use

Impact of economic factors on antibiotic prescribing and use.

In the community

People buy antibiotics and self-medicate without a doctor's prescription.

Management and implementation of regulations on prescription and sale of prescription drugs are not strict.

Using antibiotics for the wrong purpose such as using antibiotics to treat common viral diseases, using antibiotics under the recommended dose, not enough time...


People lack common medical knowledge and do not understand the need for proper diagnosis and treatment of infectious diseases.

Lack of education on the proper use of antibiotics.

Not knowing the harmful effects of inappropriate and safe antibiotic use.

Consequences of inappropriate antibiotic use

For pathogens

Increase in pathogens, antibiotic-resistant strains of bacteria.

The rapid emergence of new resistant strains.

Transmission of drug-resistant strains of bacteria from animals to humans.

For treatment

Treatment is prolonged or failed.

Researchers must find new antibiotics to replace already resistant antibiotics.

The dose must be increased or more antibiotics combined if resistant bacteria are encountered.    

Prevent antibiotic resistance

In a medical facility

Use local data on antibiotic resistance to select appropriate antibiotics. Data on drug resistance of pathogenic bacteria vary widely and depend on factors such as location, patient population, individual hospital or patient's duration of treatment, so it is important to pay attention to the data. about drug resistance in each locality to choose antibiotic treatment.

Propaganda and education activities on antibiotic use

Monitor and communicate about antibiotic resistance regularly, raise awareness about antibiotic resistance in health facilities.

Use tools, training programs, propaganda and education, and instructions on rational use of antibiotics for doctors, medical staff and patients.

Prevent infection

Vaccination against infectious diseases can be prevented.

Limit interventional procedures, invasive procedures when not necessary.

Well perform the work of preventing hospital infections.

Effective Diagnosis and treatment

Accurately identify the causative organism, consult an infectious disease specialist before prescribing. Implement good prescribing practices (GPP).

Develop guidelines for the treatment of infectious diseases, strengthen cooperation between professional organizations and specialized journals to publish evidence-based medical information.

Interventions of healthcare workers with high-risk patients

Training and education on drug information and treatment.

Strengthen retraining for doctors and pharmacists in the knowledge of rational use of antibiotics and use of information on antibiotic resistance in prescribing.

Develop a list of antibiotics used in hospitals, evaluate antibiotic use in clinical practice.

Collect and report information on treatment efficacy and adverse reactions (ADRs).

With the community

Disseminate health education through health facilities and mass media.

Education on rational use of antibiotics through mass organizations such as Women's Union, Youth Union...

Use different forms of communication in disseminating knowledge about antibiotic use.

With a drug dealer

Education on the rational use of antibiotics.

Strictly control the sale of prescription drugs.