Benign liver and biliary tract tumours

2021-05-12 03:10 PM

Tumours are from a few cm to 30cm in diameter, pale yellow in colour, impregnated with bile colour, in liver tissue but usually located near the liver capsule.

Benign liver and biliary tract tumours

Benign liver tumours

Lumpy hyperplasia

The lesion is not a tumour and is in the form of one or more lumps that resemble lumps such as cirrhosis.

The single lumpy form of the lesion is also called focal hyperplasia. Perhaps due to a developmental defect in the humanoid form, with more women having the disease than men. Lesions are usually under the shell of the liver, about a few centimetres in diameter, clearly separated from the liver tissue owner by a thin fibrous tissue border. Under the microscope, the lesion centre has fibrous tissue with fibrous walls radiating like spokes. Between the fibrous walls are normal or slightly changed liver cells. Central fibrous tissue usually contains small bile ducts scattered with the sinuses of the blood vessels. Due to the microscopic image, the lesion takes the form of a hamartoma.

The form of multiple lumpy injuries in the liver: either more or less is defined as thromboembolic hyperplasia. These lumps are several millimetres to several centimetres in diameter. The typical picture is that each lump is made up of a normal array of liver cells, separated by a capillary sinus. But the arrangement does not appear to be spindle-shaped like normal liver tissue. These lumps are not covered with fibrous tissue. They are only covered by a very thin layer of pinched and shrunken layers of liver cells.

The cause of the disease is unknown. As with the single lump form mentioned above, the disease has been reported to be associated with long-term oral use of oral contraceptives or oral steroids that increase anabolism. For some reason, more than half of all documented cases occur in patients with Felty's syndrome (a type of rheumatoid arthritis with splenomegaly, splenomegaly, foot ulcers). When the liver is heavily damaged, diffused, portal pressure may increase with bleeding due to rupture of oesophageal veins. Diagnosis is difficult through needle liver biopsy because the microscopic morphology is nonspecific.

Liver cell tumours

The benign tumour is rare, although the incidence has increased with the introduction of the oral contraceptive pill. Oestrogen is a substance that can promote the formation of certain types of tumours in humans and animals. However, the role of oestrogens in the formation of hepatocytes is not well known.

Tumours are from a few cm to 30cm in diameter, pale yellow in colour, impregnated with bile colour, in liver tissue. But they are usually located near the liver capsule, with clear limits but the shell is unknown. Sometimes the cyst has branches (such as prosthetic legs) entering the surrounding liver tissue, causing a misdiagnosis of invasive cancer.

Under a microscope, the tumour consists of rows of cells like normal liver cells (or slightly different in nuclear and cell size), sometimes with light cytoplasm. The most obvious is that the vascular sinuses are abnormally dilated and arranged, and the bile ducts are often absent. The cyst is the connective tissue that separates the tumour from the normal host. But sometimes there are defects, sometimes there is absolutely no sheath.

Hepatocellular adenoma is relatively important clinically because the tumour can cause misdiagnosis with hepatocellular carcinoma. Tumours can be broken (if the tumour is under the liver capsule), especially when the patient is pregnant, with heavy blood in the abdomen.

Other benign tumours

Cavernous angioma

Soft lump form, 1-2cm in diameter, green, easily confusing with small haemorrhagic foci, especially when the tumour is under the liver capsule. The microstructure is the same as elsewhere.

Biliary tract tumours

Small lump with diameter less than 1cm, firm, pale colour and not impregnated with bile (different from the hepatocellular tumour). Tumours include the lining of the epithelium, separated by the connective stroma. U usually does not have a complete shell, so it is often considered a hamartoma.

The sacs

Solitary sacs: are benign tumours with a diameter of 5-10cm, containing clear fluid and lined by cells like bile duct epithelial cells are shrunk and flat.

Polycystic: more common, with many small sacs 3-4cm in diameter, lined with cell-like cubes of small bile ducts. Some sacs contain greenish-brown precipitates, which may be dense bile. Polycystic liver disease is often accompanied by polycystic disease.

Related articles:

Liver Tumors

Cholangiocarcinoma, also known as bile duct cancer