Anatomy of colon birth defects

2021-05-12 04:04 PM

Diagnosis is based on the absence of neural ganglion cells between two smooth muscle layers of the narrow segment on rectal biopsy samples.

Very rare. The two most common malformations are colonic enlargement and no anus.

Enlarged colon or Hirschsprung disease

The disease causes total or partial intestinal obstruction, usually occurring in babies or young children. Children with Down syndrome are 10 times more likely to develop the disease than other children.

The colon has a narrow place where there are no Auerbach and Meissner nerve ganglion cells, the upper part of the colon is enlarged. Therefore, the disease is also called amenorrhea colon. The lack of nerve ganglion cells is usually not higher than the sigmoid colon, but in rare cases may be present in the entire colon or small intestine.

Diagnosis is based on the absence of neural ganglion cells between two smooth muscle layers of the narrow segment on rectal biopsy samples.

Evidence does not have an anus

Because the membrane between the intestine and the anus does not puncture during the development of the foetus. This diaphragm completely closes the anal canal.

The incidence of this malformation is 1/5000 newborns. It is worse if the child has other defects such as infertility, obstruction, or stenosis of the rectal canal. Sometimes there are more lines with the genitals or urinary tract.