Acute kidney damage: the cause of the damage

2021-05-06 02:13 PM

The causes of acute kidney damage (AKI) can be divided into three main causes: acute pre-kidney damage, acute renal damage, and acute post-renal damage.


The causes of acute kidney damage (AKI) can be divided into three main causes:

1. Acute pre-kidney damage to the kidneys: Due to decreased blood flow to the kidneys. This condition is often referred to as acute pre-kidney damage to reflect the cause of the external organs of the kidney. For example, acute pre-kidney damage may result from heart failure with decreased cardiac output and hypotension or conditions associated with decreased blood volume and hypotension, such as blood loss. level.

2. Acute kidney damage to the kidney: is the result of abnormalities in the kidney, including the kidney blood vessels, glomeruli or tubules.

3. Acute post-renal damage to the kidneys: is the result of obstruction of the urine-collecting system anywhere from the kidney stations to the bladder. The most common causes of extra-renal urinary obstruction are kidney stones, a result of deposition of calcium, urate, or cystine.


Pathophysiology of cardiogenic shock

Urine formation: Reabsorbed glomerular filtration

Air in and out of the lungs: pressure causes the movement of air

Mechanism of urine concentration: osmotic pressure changes in different segments of the renal tubule

Absorption and excretion of potassium through the kidneys

Nephron: The functional unit of the kidney

Estimated renal plasma flow: PAH clearance

Prothrombin activation: initiates blood clotting

Pulmonary capillary dynamics: capillary fluid exchange and pulmonary interstitial fluid dynamics

Graphical analysis of high-volume heart failure

Red blood cells: differentiation and synthesis

Calculate the glomerular filtration rate (GFR): the forces that cause the filtration process

Ammonia buffering system: excretes excess H + and creates new HCO3

Concentrated urine formation: urea contributes to increased osmotic pressure in the renal medullary

Reduced sodium chloride, dilates arterioles, increases Renin release.

Extracellular fluid distribution between interstitial space and blood vessels

The proximal tubule reabsorption: active and passive reabsorption

Origin of lymphocytes: the body's resistance to infection

Pathophysiology of fever

Acidosis causes a decrease in HCO3- / H + in renal tubular fluid: compensation mechanism of the kidney

The endocrine regulates tubular reabsorption

Sodium channel blockers: decrease the reabsorption of sodium in the manifold

Self-regulation of glomerular filtration rate and renal blood flow

Physiological anatomy of the kidneys and urinary system

The myogenic mechanism itself regulates renal blood flow and glomerular filtration rate