CO2: excreted lungs help balance metabolism

2021-05-06 10:13 AM

If the conversion rate to CO2 increases, the pCO2 also increases. Similarly, if metabolism is reduced, pCO2 also decreases. If the rate of pulmonary ventilation increases, more CO2 is excreted and the pCO2 in the extracellular fluid decreases.

 

The second method to correct the acidosis disorder is to regulate the concentration of extracellular CO2 in the lungs. The hyperventilation reduces extracellular CO2, thereby reducing the H + concentration. Conversely, hypoventilation increases extracellular CO2 leading to an increase in H + concentration.

CO2 is continuously formed in the body by intracellular metabolism. Once formed, it diffuses from the cell into the interstitial fluid, the blood and bloodstream transporting CO2 to the lungs, where it is diffused and the alveoli and out by the lung's gas exchange activity. Usually, about 1.2 mol / L CO2 is dissolved in extracellular fluid, corresponding to pCO2 of about 40mmHG

If the conversion rate to CO2 increases, the pCO2 also increases. Similarly, if metabolism is reduced, pCO2 also decreases. If the rate of pulmonary ventilation increases, more CO2 is excreted and the pCO2 in the extracellular fluid decreases. Therefore, changes in pulmonary ventilation or rate of CO2 formation by tissues may alter extracellular fluid pCO2.

 

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