Thrombosis: risk of serious embolism

2021-02-08 12:00 AM

The cause of thrombosis is often the rough endothelial surface of the blood vessel, which can be caused by atherosclerosis, infection or trauma and the very slow flow of blood in the lumen.

Thrombosis and embolism

A blood clot that forms abnormally in the lumen is called a thrombus. When this clot develops, the continuous flow of blood will wash it away, the clot that flows freely like this will cause the embolism. If the embolism of the large artery or a blood clot from the left heart can go away and block the arteries or arterioles in the brain, kidneys, and elsewhere.

If the thrombus originates in the venous system or the right heart, it will usually float to the lungs, causing pulmonary artery obstruction.

Causes of thrombosis

The causes of blood clots in humans are: (1) The rough endothelial surface of blood vessels can be caused by atherosclerosis, infection or trauma (such as those that trigger blood clotting.), and (2) the very slow flow rate of blood in the lumen also often causes blood clotting when small amounts of thrombin and other clotting factors are always produced.

Use of t-PA to dissolve intravascular clots

When tPA is added to the clot area through the catheter, it activates plasminogen into plasmin, thereby dissolving the clot. For example, if tPA is used within the first hour or after a blood clot clogs a coronary artery, there is no serious damage to the heart.


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