Current problems of medical microbiology

2021-08-27 06:12 PM

Since microbiology has matured until now, humans have been able to gradually conquer infections. But the way to conquer

In medicine, microorganisms are the cause of infections. Therefore, when considering the current importance of medical microbiology, it is necessary to mention the situation of infectious diseases.

Since ancient times, infections have been a scourge for mankind. Smallpox, plague, cholera... killed millions of people, devastated many villages and cities.

Since microbiology has matured until now, humans have been able to gradually conquer infections. But the tame path toward eradicating the infection is a long and difficult one.

The first resounding achievement occurred in 1891 when Von Behring saved a baby's life with anti-diphtheria serum, inaugurating the era of serum therapy. In fact, sera therapy has limitations and is only effective for bacterial toxin infections such as diphtheria, tetanus, gas gangrene, etc..

The second resounding achievement is the credit of G.Domagk who invented sulfonamides in 1935. But gradually sulfonamide weapons proved to be weak and unable to treat most common infections.

In 1940 Fleming, Florey and Chain invented penicillin and introduced it to the treatment that started the antibiotic era. During the past two decades, many effective antibiotics have been invented and infections can be effectively controlled. But time shows the infection is still far from resolved because resistant bacteria have been observed in the bacterial species. Fortunately, newly discovered effective antibiotics have kept resistant bacteria from growing too large to be contained. In the early 1980s, it was a fact that antibiotic-resistant bacteria appeared more and more, but newly discovered effective antibiotics became rare. Except for the quinolone antibiotics,

At present, most infections have been effectively contained, outbreaks are extinguished rapidly, but much research is still needed to control drug-resistant bacteria and find effective drugs to treat these infections. viral disease.

The way to deal with the current infection can be the simultaneous use of the following three measures:

Implement an antibiotic strategy to limit resistant bacteria.

- Continue to search for new effective antibiotics to treat bacterial diseases and develop effective antiviral drugs.

- Preparation of effective vaccines using modern techniques such as genetic engineering to prevent infections, gradually moving towards eradicating them as is the case with smallpox on a worldwide scale.

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