- Home
- Medical books
- Medical Pathology
- Genomic Imprinting
Genomic Imprinting
2021-02-24 12:00 AM
Genomic imprinting refers to the differential expression of genes based on chromo-somal inheritance from maternal versus paternal origin.
GENOMIC IMPRINTING
Genomic imprinting refers to the differential expression of genes based on chromo-somal inheritance from maternal versus paternal origin.
- In Prader-Willi syndrome, microdeletion on paternal chromosome 15 {del(15) (q11;q13)} causes intellectual disability, obesity, hypogonadism, and hypotonia.
- In Angelman syndrome, microdeletion on maternal chromosome 15 {del(15) (q11;q13)} causes intellectual disability, seizures, ataxia, and inappropriate laughter.
