Pathology of pyelonephritis

2021-01-26 12:00 AM

Pregnant women the large uterus presses on the ureter in the last months, causing ureteral pyelonephrolysis, a decrease in ureter motility due to increased progesterone.



Pyelonephritis is an inflammatory disease of the interstitial organization of the kidney caused by bacteria. The disease can affect both kidneys at the same time but can also be in only one kidney, and even in one kidney can be localized in part of the kidney or spread to the entire kidney. The disease can be acute or chronic.

Features of pyelonephritis

About the cause:

The bacteria cause direct damage, in addition to the advantageous factor is urine retention.

About disease surgery:

Combining renal pelvis damage, renal sepals and renal parenchyma that damage is the main parenchyma.

About developments:

Recurrent pyelonephritis, which is dull, if the treatment is not complete, acute pyelonephritis easily becomes chronic.


Pyelonephritis is a common pathology of the renal urinary system. Pyelonephritis accounts for 15-40% of kidney diseases and 80% of women and elderly children can get it. Particularly, acute pyelonephritis accounts for about 0.2-0.4% of diseases in the General Department of Internal Medicine at Hue Central Hospital. Acute pyelonephritis usually occurs in the age group 20-50 years, women are older than men, and up to 92% of patients have one or more favourable factors. Chronic pyelonephritis occurs more often in the age group 40-70 years. According to the author Nguyen Van Xang, Chronic pyelonephritis accounts for 30% of chronic kidney diseases.

Whole disease


The agents that cause pyelonephritis today are identified not only limited to bacteria but also fungi, parasites, and viruses.

The following pathogens can be detected in isolation

Escherichia Coli, Proteus Mirabilis, Enterobacter, Klebsiella, Staphylococcus aureus, Pseudomonas, Serratia, Bacillus, Chlamydia Trachomatis, Ureaplasma Urealyticum, gonorrhoea.

Candida Albicans, Candida Tropicalis, Adenovirus, Cytomegalovirus (CMV).

Pathway of infection:

The upstream sugar accounts for the majority of cases (97%), the bacteria will penetrate from the bottom up through the urethra. The infiltration of pathogens is facilitated by bladder-ureter reflux.

Blood sugar: In less than 3% of cases, bacteria arrive at the kidneys secondary to sepsis.

Advantageous factor

Children: Ureteral congenital malformation, pyelonephritis.

Elderly: Fibroid or prostate cancer.

Pregnant women: The large uterus presses on the ureter in the last months, causing pyelonephrolysis - ureter, decreased ureter motility due to increased progesterone.

Adults: Urinary stones, urethral stenosis, bladder-ureter reflux, diabetes mellitus.

Procedures: catheterization, cystoscopy, the above causes will stagnate urine, make it easy to get infected and keep infection.