Placental progesterone secretion

2021-06-09 02:45 PM

Progesterone contributes to the development of the foetus, increases the secretion of the fallopian tubes and the mother's uterus, providing appropriate nutrients for the development of the morula and blastocyst.

Progesterone is also essential for a successful pregnancy, in fact, it's just as important as oestrogen. Initially, it is secreted by the corpus luteum, later in life, it is secreted by the placenta.

Rates of oestrogen and progesterone secretion and human chorionic gonadotropin concentrations at different stages of pregnancy.

Figure. Rates of oestrogen and progesterone secretion and human chorionic gonadotropin concentrations at different stages of pregnancy.

Progesterone has the following effects on the normal development of pregnancy:

  1. Progesterone causes cells that nourish the embryo to attach to the endometrium.
  2. Progesterone reduces uterine contractions during pregnancy, preventing uterine contractions that cause spontaneous abortion. 
  3. Progesterone contributes to the development of the foetus, increases the secretion of the fallopian tubes and the mother's uterus, and provides appropriate nutrients for the development of the morula and blastocyst. It affects cell division in early developing embryos.
  4. Progesterone secretes oestrogen to stimulate breast growth (discussed in this chapter).

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