Janeway injuries - signs of symptoms and causes

Description

Painless, maculopapular or petechial lesions are common on the palms of the hands or soles of the feet - especially in the female or pinky tissue.

Figure. Injury Janeway

Cause

Infectious endocarditis - often seen in the acute phase of the disease.

Mechanism

The mechanism of this phenomenon is still unclear.

Janeway lesions are thought to be caused by infection with thromboembolism located in the peripheral regions. However, recent histological research suggests that immune vasculitis may play a major role in a number of lesions.

Meaning

Janeway lesions have a limited value of one marker, found only in 4–10% of patients with infectious endocarditis. If present, additional screening is needed for other signs of infectious endocarditis.