Osler's Nodes: Symptoms and Causes

2021-03-15 12:00 AM

The Osler nodule differs from the Janeway array in that it has a lining created by the immune process and vascular proliferation; however, a number of histological studies have provided supportive evidence for the embolism process.

Description

Skin nodules are hard, purple-red, light, often with a pale surface. Most found in the fingertips, toes, but also on the tissues of the hands and feet, and often painful.

Figure. Osler's nodules in infectious endocarditis.

Reason

Common

Bacterial endocarditis.

Rarely

Systemic lupus erythematosus.

Gonorrhea.

Distal infection following arterial catheter insertion.

Mechanism

Like the Janeway Plate, the mechanism of this symptom is not well known. The Osler nodule differs from the Janeway array in that it has a lining created by the immune process and vascular proliferation; however, a number of histological studies have provided supportive evidence for the embolism process.

Meaning

Found in only 10-25% of bacterial endocarditis. Poor sensitivity limits the Osler note value.