Sclerosis: signs of symptoms and causes

2021-01-26 12:00 AM

Sclerosis may be the result of the altered peripheral regulation of motor neurons in the medulla and the alteration in the activity of spinal motor neurons in response to peripheral stimuli during stretch reflexes.


Sclerosis is an increase in resistance to passive movements because of an abnormal increase in muscle tone. There are three characteristics:

The resistance is not dependent on the rate of muscle tension (resistance is the same whether fast or slow passive movement).

Strength fold and stretch evenly.

Not weak muscles.

Sclerosis is a sign of extrapyramidal disease. It is sometimes also called ductile hardening, waxy hardening, or lead duct hardening. Sclerosis can be worse with passive movement in the patient's lateral limb, a phenomenon known as active sclerosis.



Parkinson disease.

Drugs - dopamine antagonists (eg. Haloperidol, metoclopramide).

Less common

Disseminated white matter (eg. Defect infarction).

Multi-system atrophy.

Paralysis on the progressive nucleus.

Cortical and basal ganglia degeneration.